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Mitochondrial respiratory chain dysfunction modulates metalloproteases -1, -3 and -13 in human normal chondrocytes in culture

BACKGROUND: Mitochondrion has an important role in the osteoarthritis (OA) pathology. We have previously demonstrated that the alteration of the mitochondrial respiratory chain (MRC) contributes to the inflammatory response of the chondrocyte. However its implication in the process of cartilage dest...

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Autori principali: Cillero-Pastor, Berta, Rego-Pérez, Ignacio, Oreiro, Natividad, Fernandez-Lopez, Carlos, Blanco, Francisco J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750811/
https://ncbi.nlm.nih.gov/pubmed/23937653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-14-235
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