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Autophagy is a Protective Mechanism in Normal Cartilage and its Aging-related Loss is Linked with Cell Death and Osteoarthritis

OBJECTIVE: Autophagy is a process for turnover of intracellular organelles and molecules that protects cells during stress responses. This study evaluated the potential role of ULK1, an inducer of autophagy, Beclin1, a regulator of autophagy and LC3, which executes autophagy, in the development of o...

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Detalhes bibliográficos
Main Authors: Caramés, Beatriz, Taniguchi, Noboru, Otsuki, Shuhei, Blanco, Francisco J., Lotz, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838960/
https://ncbi.nlm.nih.gov/pubmed/20187128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27305
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