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Mechanical Injury Suppresses Autophagy Regulators and its Pharmacological Activation Results in Chondroprotection
OBJECTIVE: Mechanical injury induces cell death in cartilage and triggers a remodeling process that ultimately can manifest as osteoarthritis (OA). Autophagy is a process for turnover of intracellular organelles and macromolecules that protects cells during stress responses. This study determined ch...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288456/ https://ncbi.nlm.nih.gov/pubmed/22034068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33444 |
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