Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

Long interspersed nuclear element–1 (L1) retrotransposons are mobile repetitive elements that are abundant in the human genome. L1 elements propagate through RNA intermediates. In the germ line, neighboring, nonrepetitive sequences are occasionally mobilized by the L1 machinery, a process called 3′...

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Argitaratua izan da:Science
Egile Nagusiak: Tubio, Jose M. C., Li, Yilong, Ju, Young Seok, Martincorena, Inigo, Cooke, Susanna L., Tojo, Marta, Gundem, Gunes, Pipinikas, Christodoulos P., Zamora, Jorge, Raine, Keiran, Menzies, Andrew, Roman-Garcia, Pablo, Fullam, Anthony, Gerstung, Moritz, Shlien, Adam, Tarpey, Patrick S., Papaemmanuil, Elli, Knappskog, Stian, Van Loo, Peter, Ramakrishna, Manasa, Davies, Helen R., Marshall, John, Wedge, David C., Teague, Jon W., Butler, Adam P., Nik-Zainal, Serena, Alexandrov, Ludmil, Behjati, Sam, Yates, Lucy R., Bolli, Niccolo, Mudie, Laura, Hardy, Claire, Martin, Sancha, McLaren, Stuart, O'Meara, Sarah, Anderson, Elizabeth, Maddison, Mark, Gamble, Stephen, Foster, Christopher, Warren, Anne Y., Whitaker, Hayley, Brewer, Daniel, Eeles, Rosalind, Cooper, Colin, Neal, David, Lynch, Andy G., Visakorpi, Tapio, Isaacs, William B., Veer, Laura van't, Caldas, Carlos, Desmedt, Christine, Sotiriou, Christos, Aparicio, Sam, Foekens, John A., Eyfjörd, Jórunn Erla, Lakhani, Sunil R., Thomas, Gilles, Myklebost, Ola, Span, Paul N., Børresen-Dale, Anne-Lise, Richardson, Andrea L., Van de Vijver, Marc, Vincent-Salomon, Anne, Van den Eynden, Gert G., Flanagan, Adrienne M., Futreal, P. Andrew, Janes, Sam M., Bova, G. Steven, Stratton, Michael R., McDermott, Ultan, Campbell, Peter J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
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Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380235/
https://ncbi.nlm.nih.gov/pubmed/25082706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1251343
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