Sphingosine 1-Phosphate Receptor-1 Enhances Mitochondrial Function and Reduces Cisplatin-Induced Tubule Injury

Sphingosine 1-phosphate (S1P), the natural sphingolipid ligand for a family of five G protein– coupled receptors (S1P1–S1P5Rs), regulates cell survival and lymphocyte circulation. We have shown that the pan-S1PR agonist, FTY720, attenuates kidney ischemia-reperfusion injury by directly activating S1...

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Detaylı Bibliyografya
Yayımlandı:J Am Soc Nephrol
Asıl Yazarlar: Bajwa, Amandeep, Rosin, Diane L., Chroscicki, Piotr, Lee, Sangju, Dondeti, Krishna, Ye, Hong, Kinsey, Gilbert R., Stevens, Brian K., Jobin, Katarzyna, Kenwood, Brandon M., Hoehn, Kyle L., Lynch, Kevin R., Okusa, Mark D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2015
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378101/
https://ncbi.nlm.nih.gov/pubmed/25145931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013121351
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