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Sphingosine 1-Phosphate Receptor-1 Enhances Mitochondrial Function and Reduces Cisplatin-Induced Tubule Injury

Sphingosine 1-phosphate (S1P), the natural sphingolipid ligand for a family of five G protein– coupled receptors (S1P1–S1P5Rs), regulates cell survival and lymphocyte circulation. We have shown that the pan-S1PR agonist, FTY720, attenuates kidney ischemia-reperfusion injury by directly activating S1...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Am Soc Nephrol
Päätekijät: Bajwa, Amandeep, Rosin, Diane L., Chroscicki, Piotr, Lee, Sangju, Dondeti, Krishna, Ye, Hong, Kinsey, Gilbert R., Stevens, Brian K., Jobin, Katarzyna, Kenwood, Brandon M., Hoehn, Kyle L., Lynch, Kevin R., Okusa, Mark D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Nephrology 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378101/
https://ncbi.nlm.nih.gov/pubmed/25145931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013121351
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