Sphingosine 1-Phosphate Receptor-1 Enhances Mitochondrial Function and Reduces Cisplatin-Induced Tubule Injury

Sphingosine 1-phosphate (S1P), the natural sphingolipid ligand for a family of five G protein– coupled receptors (S1P1–S1P5Rs), regulates cell survival and lymphocyte circulation. We have shown that the pan-S1PR agonist, FTY720, attenuates kidney ischemia-reperfusion injury by directly activating S1...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Bajwa, Amandeep, Rosin, Diane L., Chroscicki, Piotr, Lee, Sangju, Dondeti, Krishna, Ye, Hong, Kinsey, Gilbert R., Stevens, Brian K., Jobin, Katarzyna, Kenwood, Brandon M., Hoehn, Kyle L., Lynch, Kevin R., Okusa, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378101/
https://ncbi.nlm.nih.gov/pubmed/25145931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013121351
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados