Dendritic Cell Sphingosine 1-Phosphate Receptor-3 Regulates Th1–Th2 Polarity in Kidney Ischemia–Reperfusion Injury

Dendritic cells (DCs) are central to innate and adaptive immunity of early kidney ischemia–reperfusion injury (IRI), and strategies to alter DC function may provide new therapeutic opportunities. Sphingosine 1-phosphate (S1P) modulates immunity through binding to its receptors (S1P1–5), and protecti...

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Bibliographic Details
Main Authors: Bajwa, Amandeep, Huang, Liping, Ye, Hong, Dondeti, Krishna, Song, Steven, Rosin, Diane L., Lynch, Kevin R., Lobo, Peter I., Li, Li, Okusa, Mark D.
Format: Artigo
Language:Inglês
Published: AAI 2012
Subjects:
Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433235/
https://ncbi.nlm.nih.gov/pubmed/22855711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200999
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