A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase α

The endocannabinoid 2-arachidonoylglycerol (2-AG) is predominantly biosynthesized by sn-1-diacylglycerol lipase α (DAGL-α) in the CNS. Selective inhibitors of DAGL-α will provide valuable insights in the role of 2-AG in endocannabinoid signaling processes and are potential therapeutics for the treat...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Lipid Res
Main Authors: van der Wel, Tom, Janssen, Freek J., Baggelaar, Marc P., Deng, Hui, den Dulk, Hans, Overkleeft, Herman S., van der Stelt, Mario
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2015
Fag:
Methods
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373749/
https://ncbi.nlm.nih.gov/pubmed/25684760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D056390
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker