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Systematic discovery of regulated and conserved alternative exons in the mammalian brain reveals NMD modulating chromatin regulators

Alternative splicing (AS) dramatically expands the complexity of the mammalian brain transcriptome, but its atlas remains incomplete. Here we performed deep mRNA sequencing of mouse cortex to discover and characterize alternative exons with potential functional significance. Our analysis expands the...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Yan, Qinghong, Weyn-Vanhentenryck, Sebastien M., Wu, Jie, Sloan, Steven A., Zhang, Ye, Chen, Kenian, Wu, Jia Qian, Barres, Ben A., Zhang, Chaolin
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371929/
https://ncbi.nlm.nih.gov/pubmed/25737549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502849112
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