Systematic discovery of regulated and conserved alternative exons in the mammalian brain reveals NMD modulating chromatin regulators

Alternative splicing (AS) dramatically expands the complexity of the mammalian brain transcriptome, but its atlas remains incomplete. Here we performed deep mRNA sequencing of mouse cortex to discover and characterize alternative exons with potential functional significance. Our analysis expands the...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Yan, Qinghong, Weyn-Vanhentenryck, Sebastien M., Wu, Jie, Sloan, Steven A., Zhang, Ye, Chen, Kenian, Wu, Jia Qian, Barres, Ben A., Zhang, Chaolin
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371929/
https://ncbi.nlm.nih.gov/pubmed/25737549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502849112
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