Systematic discovery of regulated and conserved alternative exons in the mammalian brain reveals NMD modulating chromatin regulators

Alternative splicing (AS) dramatically expands the complexity of the mammalian brain transcriptome, but its atlas remains incomplete. Here we performed deep mRNA sequencing of mouse cortex to discover and characterize alternative exons with potential functional significance. Our analysis expands the...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Yan, Qinghong, Weyn-Vanhentenryck, Sebastien M., Wu, Jie, Sloan, Steven A., Zhang, Ye, Chen, Kenian, Wu, Jia Qian, Barres, Ben A., Zhang, Chaolin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371929/
https://ncbi.nlm.nih.gov/pubmed/25737549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502849112
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