Systematic discovery of regulated and conserved alternative exons in the mammalian brain reveals NMD modulating chromatin regulators

Alternative splicing (AS) dramatically expands the complexity of the mammalian brain transcriptome, but its atlas remains incomplete. Here we performed deep mRNA sequencing of mouse cortex to discover and characterize alternative exons with potential functional significance. Our analysis expands the...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yan, Qinghong, Weyn-Vanhentenryck, Sebastien M., Wu, Jie, Sloan, Steven A., Zhang, Ye, Chen, Kenian, Wu, Jia Qian, Barres, Ben A., Zhang, Chaolin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371929/
https://ncbi.nlm.nih.gov/pubmed/25737549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502849112
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