Mouse Model of the OPRM1 (A118G) Polymorphism: Differential Heroin Self-Administration Behavior Compared with Wild-Type Mice

Mu-opioid receptors (MOPRs) are the target of heroin and other prescription opioids, which are currently responsible for massive addiction morbidity in the US. The gene coding for the human MOPR (OPRM1) has an important functional single nucleotide polymorphism (SNP), A118G. The OPRM1 A118G genotype...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neuropsychopharmacology
Egile Nagusiak: Zhang, Yong, Picetti, Roberto, Butelman, Eduardo R, Ho, Ann, Blendy, Julie A, Kreek, Mary Jeanne
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367451/
https://ncbi.nlm.nih.gov/pubmed/25336208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.286
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