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Dose escalation and dose preference in extended-access heroin self-administration in Lewis and Fischer rats

RATIONALE: A genetic component may be involved in different stages of the progression of drug addiction. Heroin users escalate unit doses and frequency of self-administration events over time. Rats that self-administer drugs of abuse over extended sessions escalate the amount of drug infused over da...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Picetti, Roberto, Caccavo, Jilda A., Ho, Ann, Kreek, Mary Jeanne
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359091/
https://ncbi.nlm.nih.gov/pubmed/21894484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2464-4
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