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Strain and cocaine-induced differential opioid gene expression may predispose Lewis but not Fischer rats to escalate cocaine self-administration

The aim of the present study was to investigate alterations in gene expression of opioid system components induced by extended access (18 h) cocaine self-administration and to determine the impact of genetic background in the vulnerability to escalate cocaine intake. Comparing two inbred rat strains...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Valenza, Marta, Picetti, Roberto, Yuferov, Vadim, Butelman, Eduardo R., Kreek, Mary Jeanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894495/
https://ncbi.nlm.nih.gov/pubmed/26777278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.01.004
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