Mouse Model of the OPRM1 (A118G) Polymorphism: Differential Heroin Self-Administration Behavior Compared with Wild-Type Mice

Mu-opioid receptors (MOPRs) are the target of heroin and other prescription opioids, which are currently responsible for massive addiction morbidity in the US. The gene coding for the human MOPR (OPRM1) has an important functional single nucleotide polymorphism (SNP), A118G. The OPRM1 A118G genotype...

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Bibliografiske detaljer
Udgivet i:Neuropsychopharmacology
Main Authors: Zhang, Yong, Picetti, Roberto, Butelman, Eduardo R, Ho, Ann, Blendy, Julie A, Kreek, Mary Jeanne
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367451/
https://ncbi.nlm.nih.gov/pubmed/25336208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.286
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