Mouse Model of the OPRM1 (A118G) Polymorphism: Differential Heroin Self-Administration Behavior Compared with Wild-Type Mice

Mu-opioid receptors (MOPRs) are the target of heroin and other prescription opioids, which are currently responsible for massive addiction morbidity in the US. The gene coding for the human MOPR (OPRM1) has an important functional single nucleotide polymorphism (SNP), A118G. The OPRM1 A118G genotype...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neuropsychopharmacology
Päätekijät: Zhang, Yong, Picetti, Roberto, Butelman, Eduardo R, Ho, Ann, Blendy, Julie A, Kreek, Mary Jeanne
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367451/
https://ncbi.nlm.nih.gov/pubmed/25336208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.286
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