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Mouse Model of OPRM1 (A118G) Polymorphism Increases Sociability and Dominance and Confers Resilience to Social Defeat

A single nucleotide polymorphism (SNP) in the human μ-opioid receptor gene (OPRM1 A118G) has been widely studied for its association in drug addiction, pain sensitivity, and, more recently, social behavior. The endogenous opioid system has been shown to regulate social distress and reward in a varie...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Briand, Lisa A., Hilario, Monica, Dow, Holly C., Brodkin, Edward S., Blendy, Julie A., Berton, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339361/
https://ncbi.nlm.nih.gov/pubmed/25716856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4685-14.2015
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