Mouse Model of the OPRM1 (A118G) Polymorphism: Differential Heroin Self-Administration Behavior Compared with Wild-Type Mice

Mu-opioid receptors (MOPRs) are the target of heroin and other prescription opioids, which are currently responsible for massive addiction morbidity in the US. The gene coding for the human MOPR (OPRM1) has an important functional single nucleotide polymorphism (SNP), A118G. The OPRM1 A118G genotype...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Zhang, Yong, Picetti, Roberto, Butelman, Eduardo R, Ho, Ann, Blendy, Julie A, Kreek, Mary Jeanne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367451/
https://ncbi.nlm.nih.gov/pubmed/25336208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.286
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