Mouse Model of the OPRM1 (A118G) Polymorphism: Differential Heroin Self-Administration Behavior Compared with Wild-Type Mice

Mu-opioid receptors (MOPRs) are the target of heroin and other prescription opioids, which are currently responsible for massive addiction morbidity in the US. The gene coding for the human MOPR (OPRM1) has an important functional single nucleotide polymorphism (SNP), A118G. The OPRM1 A118G genotype...

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Vydáno v:Neuropsychopharmacology
Hlavní autoři: Zhang, Yong, Picetti, Roberto, Butelman, Eduardo R, Ho, Ann, Blendy, Julie A, Kreek, Mary Jeanne
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367451/
https://ncbi.nlm.nih.gov/pubmed/25336208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.286
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