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Genetic Variation in the Behavioral Effects of Buprenorphine in Female Mice Derived from a Murine Model of the OPRM1 A118G Polymorphism
Pharmacogenetic studies have identified the non-synonymous single nucleotide polymorphism (A118G) in the human mu opioid receptor (MOR) gene (OPRM1) as a critical genetic variant capable of altering the efficacy of opioid therapeutics. To date few studies have explored the potential impact of the OP...
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| Publicado no: | Neuropharmacology |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5479141/ https://ncbi.nlm.nih.gov/pubmed/28188737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.02.005 |
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