Human Mu Opioid Receptor (OPRM1 A118G) polymorphism is associated with brain mu-opioid receptor binding potential in smokers

Evidence points to the endogenous opioid system, and the mu-opioid receptor (MOR) in particular, in mediating the rewarding effects of drugs of abuse, including nicotine. A single nucleotide polymorphism (SNP) in the human MOR gene (OPRM1 A118G) has been shown to alter receptor protein level in prec...

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Detalhes bibliográficos
Main Authors: Ray, Riju, Ruparel, Kosha, Newberg, Andrew, Wileyto, E. Paul, Loughead, James W., Divgi, Chaitanya, Blendy, Julie A., Logan, Jean, Zubieta, Jon-Kar, Lerman, Caryn
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107291/
https://ncbi.nlm.nih.gov/pubmed/21576462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018699108
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