PCTAIRE1-Knockdown Sensitizes Cancer Cells to TNF Family Cytokines

While PCTAIRE1/PCTK1/Cdk16 is overexpressed in malignant cells and is crucial in tumorigenesis, its function in apoptosis remains unclear. Here we investigated the role of PCTAIRE1 in apoptosis, especially in the extrinsic cell death pathway. Gene-knockdown of PCTAIRE1 sensitized prostate cancer PPC...

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Bibliographic Details
Published in:PLoS One
Main Authors: Yanagi, Teruki, Shi, Ranxin, Aza-Blanc, Pedro, Reed, John C., Matsuzawa, Shu-ichi
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366397/
https://ncbi.nlm.nih.gov/pubmed/25790448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119404
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