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PCTAIRE1-Knockdown Sensitizes Cancer Cells to TNF Family Cytokines

While PCTAIRE1/PCTK1/Cdk16 is overexpressed in malignant cells and is crucial in tumorigenesis, its function in apoptosis remains unclear. Here we investigated the role of PCTAIRE1 in apoptosis, especially in the extrinsic cell death pathway. Gene-knockdown of PCTAIRE1 sensitized prostate cancer PPC...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yanagi, Teruki, Shi, Ranxin, Aza-Blanc, Pedro, Reed, John C., Matsuzawa, Shu-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366397/
https://ncbi.nlm.nih.gov/pubmed/25790448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119404
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