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PCTAIRE1-Knockdown Sensitizes Cancer Cells to TNF Family Cytokines

While PCTAIRE1/PCTK1/Cdk16 is overexpressed in malignant cells and is crucial in tumorigenesis, its function in apoptosis remains unclear. Here we investigated the role of PCTAIRE1 in apoptosis, especially in the extrinsic cell death pathway. Gene-knockdown of PCTAIRE1 sensitized prostate cancer PPC...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Yanagi, Teruki, Shi, Ranxin, Aza-Blanc, Pedro, Reed, John C., Matsuzawa, Shu-ichi
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366397/
https://ncbi.nlm.nih.gov/pubmed/25790448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119404
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