Lipid Nanoparticle-mediated siRNA Transfer Against PCTAIRE1/PCTK1/Cdk16 Inhibits In Vivo Cancer Growth

PCTAIRE1/CDK16/PCTK1 plays critical roles in cancer cell proliferation and antiapoptosis. To advance our previously published in vitro results with PCTAIRE1 silencing, we examined the in vivo therapeutic potential of this approach by using small interfering RNA (siRNA) encapsulated by lipid nanopart...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Ther Nucleic Acids
Päätekijät: Yanagi, Teruki, Tachikawa, Kiyoshi, Wilkie-Grantham, Rachel, Hishiki, Asami, Nagai, Ko, Toyonaga, Ellen, Chivukula, Pad, Matsuzawa, Shu-ichi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5022131/
https://ncbi.nlm.nih.gov/pubmed/27351680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.40
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