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PCTAIRE1-Knockdown Sensitizes Cancer Cells to TNF Family Cytokines

While PCTAIRE1/PCTK1/Cdk16 is overexpressed in malignant cells and is crucial in tumorigenesis, its function in apoptosis remains unclear. Here we investigated the role of PCTAIRE1 in apoptosis, especially in the extrinsic cell death pathway. Gene-knockdown of PCTAIRE1 sensitized prostate cancer PPC...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Yanagi, Teruki, Shi, Ranxin, Aza-Blanc, Pedro, Reed, John C., Matsuzawa, Shu-ichi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366397/
https://ncbi.nlm.nih.gov/pubmed/25790448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119404
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