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Deregulation of DNA Double-Strand Break Repair in Multiple Myeloma: Implications for Genome Stability

Multiple myeloma (MM) is a hematological malignancy characterized by frequent chromosome abnormalities. However, the molecular basis for this genome instability remains unknown. Since both impaired and hyperactive double strand break (DSB) repair pathways can result in DNA rearrangements, we investi...

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Herrero, Ana B., San Miguel, Jesús, Gutierrez, Norma C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366222/
https://ncbi.nlm.nih.gov/pubmed/25790254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121581
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