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Double-strand break repair-adox: Restoration of suppressed double-strand break repair during mitosis induces genomic instability

Double-strand breaks (DSBs) are one of the severest types of DNA damage. Unrepaired DSBs easily induce cell death and chromosome aberrations. To maintain genomic stability, cells have checkpoint and DSB repair systems to respond to DNA damage throughout most of the cell cycle. The failure of this pr...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cancer Sci
Asıl Yazarlar: Terasawa, Masahiro, Shinohara, Akira, Shinohara, Miki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317954/
https://ncbi.nlm.nih.gov/pubmed/25287622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12551
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