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Deregulation of DNA Double-Strand Break Repair in Multiple Myeloma: Implications for Genome Stability

Multiple myeloma (MM) is a hematological malignancy characterized by frequent chromosome abnormalities. However, the molecular basis for this genome instability remains unknown. Since both impaired and hyperactive double strand break (DSB) repair pathways can result in DNA rearrangements, we investi...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Herrero, Ana B., San Miguel, Jesús, Gutierrez, Norma C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366222/
https://ncbi.nlm.nih.gov/pubmed/25790254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121581
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