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Deregulation of DNA Double-Strand Break Repair in Multiple Myeloma: Implications for Genome Stability
Multiple myeloma (MM) is a hematological malignancy characterized by frequent chromosome abnormalities. However, the molecular basis for this genome instability remains unknown. Since both impaired and hyperactive double strand break (DSB) repair pathways can result in DNA rearrangements, we investi...
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| Udgivet i: | PLoS One |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366222/ https://ncbi.nlm.nih.gov/pubmed/25790254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121581 |
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