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Deregulation of DNA Double-Strand Break Repair in Multiple Myeloma: Implications for Genome Stability

Multiple myeloma (MM) is a hematological malignancy characterized by frequent chromosome abnormalities. However, the molecular basis for this genome instability remains unknown. Since both impaired and hyperactive double strand break (DSB) repair pathways can result in DNA rearrangements, we investi...

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Vydáno v:PLoS One
Hlavní autoři: Herrero, Ana B., San Miguel, Jesús, Gutierrez, Norma C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366222/
https://ncbi.nlm.nih.gov/pubmed/25790254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121581
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