Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells

Plumbagin (PLB) has been shown to have anticancer activities in animal models, but the role of PLB in prostate cancer treatment is unclear. This study aimed to investigate the effects of PLB on apoptosis and autophagy and the underlying mechanisms in human prostate cancer cell lines PC-3 and DU145....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zhou, Zhi-Wei, Li, Xing-Xiao, He, Zhi-Xu, Pan, Shu-Ting, Yang, Yinxue, Zhang, Xueji, Chow, Kevin, Yang, Tianxin, Qiu, Jia-Xuan, Zhou, Qingyu, Tan, Jun, Wang, Dong, Zhou, Shu-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366042/
https://ncbi.nlm.nih.gov/pubmed/25834399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S75976
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados