Silica nanoparticles induce autophagy and endothelial dysfunction via the PI3K/Akt/mTOR signaling pathway

Although nanoparticles have a great potential for biomedical applications, there is still a lack of a correlative safety evaluation on the cardiovascular system. This study is aimed to clarify the biological behavior and influence of silica nanoparticles (Nano-SiO(2)) on endothelial cell function. T...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Duan, Junchao, Yu, Yongbo, Yu, Yang, Li, Yang, Wang, Ji, Geng, Weijia, Jiang, Lizhen, Li, Qiuling, Zhou, Xianqing, Sun, Zhiwei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227623/
https://ncbi.nlm.nih.gov/pubmed/25395850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S71074
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