Residues required for phosphorylation of translation initiation factor eIF2α under diverse stress conditions are divergent between yeast and human

PERK, PKR, HRI and GCN2 are the four mammalian kinases that phosphorylate the α subunit of the eukaryotic translation initiation factor 2 (eIF2α) on Ser51. This phosphorylation event is conserved among many species and attenuates protein synthesis in response to diverse stress conditions. In contras...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Biochem Cell Biol
Egile Nagusiak: Majumder, Mithu, Mitchell, Daniel, Merkulov, Sergei, Wu, Jing, Guan, Bo-Jhih, Snider, Martin D., Krokowski, Dawid, Yee, Vivien C., Hatzoglou, Maria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365977/
https://ncbi.nlm.nih.gov/pubmed/25541374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2014.12.004
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