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Residues required for phosphorylation of translation initiation factor eIF2α under diverse stress conditions are divergent between yeast and human

PERK, PKR, HRI and GCN2 are the four mammalian kinases that phosphorylate the α subunit of the eukaryotic translation initiation factor 2 (eIF2α) on Ser51. This phosphorylation event is conserved among many species and attenuates protein synthesis in response to diverse stress conditions. In contras...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Biochem Cell Biol
Prif Awduron: Majumder, Mithu, Mitchell, Daniel, Merkulov, Sergei, Wu, Jing, Guan, Bo-Jhih, Snider, Martin D., Krokowski, Dawid, Yee, Vivien C., Hatzoglou, Maria
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365977/
https://ncbi.nlm.nih.gov/pubmed/25541374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2014.12.004
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