Residues required for phosphorylation of translation initiation factor eIF2α under diverse stress conditions are divergent between yeast and human

PERK, PKR, HRI and GCN2 are the four mammalian kinases that phosphorylate the α subunit of the eukaryotic translation initiation factor 2 (eIF2α) on Ser51. This phosphorylation event is conserved among many species and attenuates protein synthesis in response to diverse stress conditions. In contras...

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Bibliografski detalji
Izdano u:Int J Biochem Cell Biol
Glavni autori: Majumder, Mithu, Mitchell, Daniel, Merkulov, Sergei, Wu, Jing, Guan, Bo-Jhih, Snider, Martin D., Krokowski, Dawid, Yee, Vivien C., Hatzoglou, Maria
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365977/
https://ncbi.nlm.nih.gov/pubmed/25541374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2014.12.004
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