eIF2α Phosphorylation Tips the Balance to Apoptosis during Osmotic Stress

Regulation of cell volume is of great importance because persistent swelling or shrinkage leads to cell death. Tissues experience hypertonicity in both physiological (kidney medullar cells) and pathological states (hypernatremia). Hypertonicity induces an adaptive gene expression program that leads...

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Detalhes bibliográficos
Main Authors: Bevilacqua, Elena, Wang, Xinglong, Majumder, Mithu, Gaccioli, Francesca, Yuan, Celvie L., Wang, Chuanping, Zhu, Xiongwei, Jordan, Lindsay E., Scheuner, Donalyn, Kaufman, Randal J., Koromilas, Antonis E., Snider, Martin D., Holcik, Martin, Hatzoglou, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878040/
https://ncbi.nlm.nih.gov/pubmed/20338999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.109439
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