Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity

Cells respond to shrinkage induced by increased extracellular osmolarity via programmed changes in gene transcription and mRNA translation. The immediate response to this stress includes the induction of expression of the neutral amino acid transporter SNAT2. Increased SNAT2-mediated uptake of neutr...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Krokowski, Dawid, Jobava, Raul, Guan, Bo-Jhih, Farabaugh, Kenneth, Wu, Jing, Majumder, Mithu, Bianchi, Massimiliano G., Snider, Martin D., Bussolati, Ovidio, Hatzoglou, Maria
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Gene Regulation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505033/
https://ncbi.nlm.nih.gov/pubmed/26041779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.636217
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