Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells

Approximately half of poor prognosis neuroblastomas (NBs) are characterized by pathognomonic MYCN gene amplification and MYCN over‐expression. Here we present data showing that short‐interfering RNA mediated depletion of the protein arginine methyltransferase 5 (PRMT5) in cell‐lines representative o...

詳細記述

保存先:
書誌詳細
出版年:Mol Oncol
主要な著者: Park, Ji Hyun, Szemes, Marianna, Vieira, Gabriella Cunha, Melegh, Zsombor, Malik, Sally, Heesom, Kate J., Von Wallwitz-Freitas, Laura, Greenhough, Alexander, Brown, Keith W., Zheng, Y. George, Catchpoole, Daniel, Deery, Michael J., Malik, Karim
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2014
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359099/
https://ncbi.nlm.nih.gov/pubmed/25475372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.10.015
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