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Transcriptomic Analyses of MYCN-Regulated Genes in Anaplastic Wilms’ Tumour Cell Lines Reveals Oncogenic Pathways and Potential Therapeutic Vulnerabilities

SIMPLE SUMMARY: Wilms’ tumour (WT) is one of the most common solid paediatric malignancies and arises in the developing kidney. Treatment of most WTs is relatively successful, with the notable exception of tumours with anaplastic histology. Anaplastic WT survival rates can be as low as 30–50%, empha...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Szemes, Marianna, Melegh, Zsombor, Bellamy, Jacob, Park, Ji Hyun, Chen, Biyao, Greenhough, Alexander, Catchpoole, Daniel, Malik, Karim
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915280/
https://ncbi.nlm.nih.gov/pubmed/33562123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13040656
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