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Transcriptomic Analyses of MYCN-Regulated Genes in Anaplastic Wilms’ Tumour Cell Lines Reveals Oncogenic Pathways and Potential Therapeutic Vulnerabilities

SIMPLE SUMMARY: Wilms’ tumour (WT) is one of the most common solid paediatric malignancies and arises in the developing kidney. Treatment of most WTs is relatively successful, with the notable exception of tumours with anaplastic histology. Anaplastic WT survival rates can be as low as 30–50%, empha...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Szemes, Marianna, Melegh, Zsombor, Bellamy, Jacob, Park, Ji Hyun, Chen, Biyao, Greenhough, Alexander, Catchpoole, Daniel, Malik, Karim
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915280/
https://ncbi.nlm.nih.gov/pubmed/33562123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13040656
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