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A Wnt-BMP4 Signaling Axis Induces MSX and NOTCH Proteins and Promotes Growth Suppression and Differentiation in Neuroblastoma

The Wnt and bone morphogenetic protein (BMP) signaling pathways are known to be crucial in the development of neural crest lineages, including the sympathetic nervous system. Surprisingly, their role in paediatric neuroblastoma, the prototypic tumor arising from this lineage, remains relatively unch...

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Pubblicato in:Cells
Autori principali: Szemes, Marianna, Melegh, Zsombor, Bellamy, Jacob, Greenhough, Alexander, Kollareddy, Madhu, Catchpoole, Daniel, Malik, Karim
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140810/
https://ncbi.nlm.nih.gov/pubmed/32210188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030783
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