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A Wnt-BMP4 Signaling Axis Induces MSX and NOTCH Proteins and Promotes Growth Suppression and Differentiation in Neuroblastoma

The Wnt and bone morphogenetic protein (BMP) signaling pathways are known to be crucial in the development of neural crest lineages, including the sympathetic nervous system. Surprisingly, their role in paediatric neuroblastoma, the prototypic tumor arising from this lineage, remains relatively unch...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Szemes, Marianna, Melegh, Zsombor, Bellamy, Jacob, Greenhough, Alexander, Kollareddy, Madhu, Catchpoole, Daniel, Malik, Karim
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140810/
https://ncbi.nlm.nih.gov/pubmed/32210188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030783
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