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A Wnt-BMP4 Signaling Axis Induces MSX and NOTCH Proteins and Promotes Growth Suppression and Differentiation in Neuroblastoma

The Wnt and bone morphogenetic protein (BMP) signaling pathways are known to be crucial in the development of neural crest lineages, including the sympathetic nervous system. Surprisingly, their role in paediatric neuroblastoma, the prototypic tumor arising from this lineage, remains relatively unch...

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Détails bibliographiques
Publié dans:Cells
Auteurs principaux: Szemes, Marianna, Melegh, Zsombor, Bellamy, Jacob, Greenhough, Alexander, Kollareddy, Madhu, Catchpoole, Daniel, Malik, Karim
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140810/
https://ncbi.nlm.nih.gov/pubmed/32210188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030783
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