Evaluation of CYP2D6 enzyme activity using a Dextromethorphan Breath Test in Women Receiving Adjuvant Tamoxifen

BACKGROUND: In tamoxifen-treated patients, breast cancer recurrence differs according to CYP2D6 genotype and endoxifen steady state concentrations (Endx Css). The 13Cdextromethorphan breath test (DM-BT), labeled with 13C at the O-CH3 moiety, measures CYP2D6 enzyme activity. We sought to examine the...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Pharmacogenet Genomics
Autori principali: Safgren, Stephanie L., Suman, Vera J., Kosel, Matthew L., Gilbert, Judith A, Buhrow, Sarah A., Black, John L., Northfelt, Donald W., Modak, Anil S., Rosen, David, Ingle, James N., Ames, Matthew M., Reid, Joel M., Goetz, Matthew P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356640/
https://ncbi.nlm.nih.gov/pubmed/25714002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000121
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi