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SULT1A1, CYP2C19 and disease-free survival in early breast cancer patients receiving tamoxifen
AIM: Tamoxifen biotransformation to endoxifen, a potent antiestrogen, is catalyzed by CYP2D6. In addition, CYP2C19 and SULT1A1 have also been implicated in the metabolism of tamoxifen. We sought to evaluate the importance of SULT1A1 copy number and CYP2C19*17 on disease-free survival (DFS) in postme...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2011
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235041/ https://ncbi.nlm.nih.gov/pubmed/21961651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.11.97 |
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