ロード中...

Loss of sclerostin promotes osteoarthritis in mice via β-catenin-dependent and -independent Wnt pathways

INTRODUCTION: Sclerostin is a Wnt inhibitor produced by osteocytes that regulates bone formation. Because bone tissue contributes to the development of osteoarthritis (OA), we investigated the role of sclerostin in bone and cartilage in a joint instability model in mice. METHODS: Ten-week-old SOST-k...

詳細記述

保存先:
書誌詳細
出版年:Arthritis Res Ther
主要な著者: Bouaziz, Wafa, Funck-Brentano, Thomas, Lin, Hilène, Marty, Caroline, Ea, Hang-Korng, Hay, Eric, Cohen-Solal, Martine
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355467/
https://ncbi.nlm.nih.gov/pubmed/25656376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0540-6
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!