Loading...

Anti-Sclerostin Antibodies in Osteoporosis and Other Bone Diseases

The Wnt pathway is a key element of bone remodeling; its activation stimulates bone formation and inhibits bone resorption. The discovery of sclerostin, a natural antagonist of the Wnt pathway, promoted the development of romosozumab, a human monoclonal antibody directed against sclerostin, as well...

Full description

Saved in:
Bibliographic Details
Published in:J Clin Med
Main Authors: Fabre, Stéphanie, Funck-Brentano, Thomas, Cohen-Solal, Martine
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694131/
https://ncbi.nlm.nih.gov/pubmed/33114755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9113439
Tags: Add Tag
No Tags, Be the first to tag this record!