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Anti-Sclerostin Antibodies in Osteoporosis and Other Bone Diseases
The Wnt pathway is a key element of bone remodeling; its activation stimulates bone formation and inhibits bone resorption. The discovery of sclerostin, a natural antagonist of the Wnt pathway, promoted the development of romosozumab, a human monoclonal antibody directed against sclerostin, as well...
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| Udgivet i: | J Clin Med |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7694131/ https://ncbi.nlm.nih.gov/pubmed/33114755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9113439 |
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