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Anti-Sclerostin Antibodies in Osteoporosis and Other Bone Diseases

The Wnt pathway is a key element of bone remodeling; its activation stimulates bone formation and inhibits bone resorption. The discovery of sclerostin, a natural antagonist of the Wnt pathway, promoted the development of romosozumab, a human monoclonal antibody directed against sclerostin, as well...

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Dades bibliogràfiques
Publicat a:J Clin Med
Autors principals: Fabre, Stéphanie, Funck-Brentano, Thomas, Cohen-Solal, Martine
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694131/
https://ncbi.nlm.nih.gov/pubmed/33114755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9113439
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