Cortical Efferents Lacking Mutant huntingtin Improve Striatal Neuronal Activity and Behavior in a Conditional Mouse Model of Huntington's Disease

Abnormal electrophysiological activity in the striatum, which receives dense innervation from the cerebral cortex, is believed to set the stage for the behavioral phenotype observed in Huntington's disease (HD), a neurodegenerative condition caused by mutation of the huntingtin (mhtt) protein....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Estrada-Sánchez, Ana María, Burroughs, Courtney L., Cavaliere, Stephen, Barton, Scott J., Chen, Shirley, Yang, X. William, Rebec, George V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2015
Aiheet:
Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355206/
https://ncbi.nlm.nih.gov/pubmed/25762686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2812-14.2015
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia