Cellular Localization of Huntingtin in Striatal and Cortical Neurons in Rats: Lack of Correlation with Neuronal Vulnerability in Huntington’s Disease

Immunohistochemistry and single-cell RT-PCR were used to characterize the localization of huntingtin and/or its mRNA in the major types of striatal neurons and in corticostriatal projection neurons in rats. Single-label immunohistochemical studies revealed that striatum contains scattered large neur...

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Udgivet i:J Neurosci
Main Authors: Fusco, Francesca R., Chen, Quan, Lamoreaux, William J., Figueredo-Cardenas, Griselle, Jiao, Yun, Coffman, Jonathan A., Surmeier, D. James, Honig, Marcia G., Carlock, Leon R., Reiner, Anton
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1999
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786020/
https://ncbi.nlm.nih.gov/pubmed/9952397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-04-01189.1999
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