Striatal parvalbuminergic neurons are lost in Huntington's disease: implications for dystonia

Although dystonia represents a major source of motor disability in Huntington's disease (HD), its pathophysiology remains unknown. Because recent animal studies indicate that loss of parvalbuminergic (PARV+) striatal interneurons can cause dystonia, we investigated if loss of PARV+ striatal int...

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Detalhes bibliográficos
Main Authors: Reiner, Anton, Shelby, Evan, Wang, Hongbing, DeMarch, Zena, Deng, Yunping, Guley, Natalie Hart, Hogg, Virginia, Roxburgh, Richard, Tippett, Lynette J, Waldvogel, Henry J, Faull, Richard LM
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812318/
https://ncbi.nlm.nih.gov/pubmed/24014043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.25624
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