Cortical Efferents Lacking Mutant huntingtin Improve Striatal Neuronal Activity and Behavior in a Conditional Mouse Model of Huntington's Disease

Abnormal electrophysiological activity in the striatum, which receives dense innervation from the cerebral cortex, is believed to set the stage for the behavioral phenotype observed in Huntington's disease (HD), a neurodegenerative condition caused by mutation of the huntingtin (mhtt) protein....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Estrada-Sánchez, Ana María, Burroughs, Courtney L., Cavaliere, Stephen, Barton, Scott J., Chen, Shirley, Yang, X. William, Rebec, George V.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355206/
https://ncbi.nlm.nih.gov/pubmed/25762686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2812-14.2015
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados