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Comparative in vitro and in vivo pharmacological investigation of platinum(IV) complexes as novel anticancer drug candidates for oral application

Platinum(IV) complexes are promising candidates as prodrugs for oral application in anticancer chemotherapy. However, only a few Pt(IV) compounds entered (pre)clinical trials, e.g. satraplatin, while most of the others were only tested in vitro. Aim of the study was investigation of the in vivo phar...

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Bibliografski detalji
Izdano u:J Biol Inorg Chem
Glavni autori: Theiner, Sarah, Varbanov, Hristo P., Galanski, Mathea Sophia, Egger, Alexander E., Berger, Walter, Heffeter, Petra, Keppler, Bernhard K.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351919/
https://ncbi.nlm.nih.gov/pubmed/25413442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-014-1214-6
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