Hyperplastic Discs Differentially Regulates the Transcriptional Outputs of Hedgehog Signaling

Hedgehog (Hh) acts as a morphogen to activate the transcription of diverse target genes via its downstream effector Cubitus interruptus (Ci). Currently, it is less understood how Ci recruits cofactors to activate transcription. Here we report that hyperplastic discs (hyd), an E3 ubiquitin ligase, ca...

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Publicat a:Mech Dev
Autors principals: Wang, Guolun, Tang, Xiaofang, Chen, Yujie, Cao, Jun, Huang, Qinzhu, Ling, Xuemei, Ren, Wenyan, Liu, Songqing, Wu, Yihui, Ray, Lorraine, Lin, Xinhua
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351657/
https://ncbi.nlm.nih.gov/pubmed/24854243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2014.05.002
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